摘要
目的总结儿童性早熟的临床特点,提高临床儿保科医师对儿童性早熟的认识。方法回顾性分析我院儿保科2006年1月月至2010年2月诊断明确的性早熟儿童42例的病例临床资料。结果女孩:男孩=10:1;真性性早熟19例,假性性早熟17例,部分性性早熟6例。真性性早熟儿童多数表现为身高增速,骨龄提前,性腺增大,促性腺激素释放激素(LHRH)兴奋试验阳性。假性性早熟:多数可以问及可疑诱因,部分患儿有身高增速,但骨龄提前、性腺增大不明显。LHRH兴奋试验阴性。结论性早熟儿童女孩明显多于男孩,女孩真性性早熟多数为特发性,多数性早熟儿童有相应诱因。骨龄测定、性腺B超、LHRH兴奋试验在性早熟鉴别诊断中具有重要意义。
Objective To summarize the clinical features of precocious puberty in order to improve clinical understanding of pediatric physicians.Methods The clinical data of 42 cases of precocious puberty in pediatric department of this hospital from January 2006 to February 2010 were retrospectively reviewed and analyzed.Results Among these 42 childish patients,19 cases suffered from precocious puberty,17 cases of pseudo precocious puberty and 6 cases of partial precocious puberty and the ratio of girls to boys was 10 ： 1.Precocious puberty in majority of children was manifested as acceleration in height growth,in advance of bone age,enlargement of gonads and positive stimulation of luteinizing hormone release test（LHRH）.In cases of pseudo-precocious puberty,suspicious inducing factors could be found in most of them,some of them with accerated height growth and advanced bone age,and enlargement of gonads is not obvious.LHRH stimulation test was negative.Conclusion In precocious children,girls are more prevalent than boys,precocious puberty is mostly idiopathic in girls.The majority of children with precocious puberty have related inducing factors.The determination of bone age,gonadal BUS and LHRH stimulation test are important in differential diagnosis of precocious puberty in children.
出处
《临床和实验医学杂志》
2011年第3期189-190,共2页
Journal of Clinical and Experimental Medicine
关键词
儿童
性早熟
特点
病因
诊断
Children
Pediatric physicians
Feature
Cases
Diagnosis
