摘要
乙型肝炎(乙肝)相关性肾炎作为最常见的并发症之一常见于慢性乙肝病毒感染患者。虽部分乙肝相关性肾炎患者可自行缓解,并维持肾功能正常,但仍有部分患者发展为肾功能不全,最终进入透析阶段,故进一步研究其有效治疗方法甚为重要。目前已有多种药物用于治疗乙肝相关性肾炎,如激素、干扰素、拉米夫定等,但对于确切疗效仍有争议。现将乙肝相关性肾炎发病机制及治疗的研究进展作一总结。
Summary ： HBV associated glomerulonephritis （ HBV-GN ） is one of the most commoncomplication of patients with chronic HBV infection. The pathogenetic mechanisms by which individuals with chronic HBV infection devel- op nephropathy are not clearly defined. Although the natural history of the disease tends often to remission with preservation of renal function, there are still some patients who had developed chronic renal failure and had to dial- ysis, this had pushed investigators to search for more specific and effective therapy for this disease. Various thera- peutic approaches have been used for HBV-GN, which including corticosteroids, thymic estracts, interferon （ IFN）, and lamivudine but their effecaeies are still arguable. This paper is aimed to summarize the recent advances in the pathogenesis and therapy of Hepatitis B virus associated glomerulonephritis.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2011年第2期103-104,共2页
Chinese Journal of Practical Internal Medicine
关键词
乙型肝炎病毒
肾炎
Hepatitis B virus
glomerulonephritis
