摘要
目的观察吴氏发泡膏穴位贴敷联合舒利迭吸入防治缓解期儿童哮喘的临床疗效及其对免疫功能的影响。方法将80例哮喘缓解期患儿随机分成治疗组和对照组各40例,两组均正规吸入舒利迭50μg/100μg,视病情每日1~2次,共6个月,治疗组在此基础上于三伏期给予吴氏发泡膏穴位贴敷,观察两组患儿临床疗效、治疗前后症状评分变化及血清总免疫球蛋白E(IgE)、白细胞介素4(IL-4)、干扰素γ(IFN-γ)等指标的变化。结果治疗组总有效率95.0%,对照组为80.0%,临床疗效治疗组优于对照组(P<0.05)。治疗组IFN-γ升高水平及总IgE、IL-4、症状评分下降水平优于对照组(P<0.05或P<0.01)。结论吴氏发泡膏穴位贴敷联合舒利迭吸入能改善哮喘患儿免疫功能,有效防治儿童哮喘。
Objective To observe the effect of acupoint application with Wu's Blistering Plaster combined with seretide inhalation in preventing and treating children with asthma in remission stage and to study its influence on immune function.Methods Eighty cases of children with asthma in remission stage were randomized into two groups,40 in treatment group and 40 in control group.Both groups were treated with seretide inhalation 50μg/100μg,one or two times a day for 6 months,based on which,the treatment group was treated with Wu's Blistering Plaster for acupoint application in dog-days.The effect and changes in symptom scores of both groups were observed,and serum IgE,IL-4,and IFN-γ were determined before and after treatment.Results The total effective rate of the treatment group and control group was 95.0% and 80.0% respectively,with significant difference(P0.05).The treatment group was superior to the control group in increase of IFN-γ and decrease of total IgE and IL-4(P0.05 or P0.01).Conclusion Acupoint application with Wu's Blistering Plaster combined with seretide inhalation is effective in improving the immune function of asthma children and its good at preventing and treating asthma.
出处
《中医杂志》
CSCD
北大核心
2011年第4期314-316,共3页
Journal of Traditional Chinese Medicine
基金
南通市科技局社会发展科研基金资助项目(S9917)
关键词
哮喘缓解期
舒利迭
吴氏发泡膏
穴位贴敷
asthma in remission stage
seretide
Wu's Blistering Plaster
acupoint application