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生芦润燥汤治疗干燥综合征临床疗效研究 被引量:12

Clinical research on the effect of Shenglu Runzao decoction on treating Sjgren's syndrome
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摘要 目的探讨生芦润燥汤治疗干燥综合征的临床疗效。方法选取2007年5月至2008年12月上海中医药大学附属市中医医院风湿科及口腔科门诊收治的60例干燥综合征患者,随机分为试验组和对照组,每组30例。试验组服用生芦润燥汤治疗,对照组服用硫酸羟氯喹治疗,两组疗程均为12个月。治疗期间每3个月随访1次,观察并记录两组患者治疗前后的症状、体征及实验室检查结果。结果试验组疗效与对照组疗效有显著差异(P<0.01);在改善症状、体征和中医征候方面,试验组明显优于对照组(P<0.01)。结论生芦润燥汤治疗干燥综合征有显著疗效。 Objective To investigate the clinical effects and feasibility of Shenglu Runzao decoction for the treatment of Sjgren's syndrome. Methods Sixty patients suffering from Sjgren's syndrome were divided into two groups randomly. Thirty patients were treated with Shenglu Runzao decoction (experimental group). Thirty patients were treated with hydroxychloroquine (control group). The clinical symptoms,signs and the laboratory data were collected before and after treatment. Results The total effective rate with experimental group was significantly higher than that of control group (P 0.01). In improving the main symptoms,signs and indications of Traditional Chinese Medicine,the experimental group was obviously superior to that of control group (P 0.01). Conclusion In the treatment of Sjgren's syndrome,Shenglu Runzao Tang has remarkable curative effect and important value of clinical applications.
作者 宣静 沈丕安
机构地区 上海市中医医院
出处 《中国实用口腔科杂志》 CAS 2010年第12期739-740,共2页 Chinese Journal of Practical Stomatology
关键词 干燥综合征 生芦润燥汤 硫酸羟氯喹 Sjgren's syndrome Shenglu Runzao decoction hydroxychloroquine
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参考文献3

  • 1董怡.2002年修订的干燥综合征国际分类(诊断)标准.中华风湿病学杂志,2002,6(4):257-257.
  • 2郑筱萸.中药新药临床研究指导原则[M].北京:中国中医药出版社,1997:231-2
  • 3李洁萍.临床疾病诊疗常规[M].上海:中国教育出版社,1998:89.

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