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钯催化交叉偶联反应及其在有机合成中的应用

Palladium-Catalyzed Cross Coupling and its Applications in Organic Synthesis
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摘要 2010年诺贝尔化学奖由三位杰出的有机化学家,理查德.海克(Richard Heck)、根岸英一(Ei-ichiNegishi)和铃木章(Akira Suzuki)分享,他们研究的钯催化交叉偶联反应成为构建有机化合物分子中碳-碳单键的重要反应,对于学术研究产生了重要的影响。由于反应条件温和,化学选择性高而被广泛应用于复杂的药物和生物活性物质的工业生产。 Three researchers,Professor Richard Heck,Professor Ei-ichi Negishi and Professor Akira Suzuki share 2010 Nobel Prize in Chemistry.Their discoveries of palladium-catalyzed cross coupling in organic syntheses are the important reactions by which carbon-carbon single bonds are formed and have had great impact on academic research.Because the reactions can be run under mild conditions and are highly chemoselective,they have been widely used in many industrial chemical processes for the synthesis of complicated pharmaceuticals and other biologically active compounds.
作者 匡华
出处 《江苏技术师范学院学报》 2010年第12期8-13,共6页 Journal of Jiangsu Teachers University of Technology
关键词 钯催化交叉偶联反应 HECK反应 Negishi反应 SUZUKI反应 Palladium-Catalyzed Cross Coupling Heck reaction Negishi reaction Suzuki reaction
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参考文献22

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