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肿瘤细胞减灭术后紫杉醇联合卡铂治疗原发性输卵管癌24例 被引量:3

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摘要 目的:探讨肿瘤细胞减灭术后辅以紫杉醇和卡铂(TP)联合治疗原发性输卵管癌的效果。方法:原发性输卵管癌24例均行肿瘤细胞减灭术,术后给予紫杉醇联合卡铂化疗6-8疗程,统计分析患者临床缓解情况、生存时间及预后影响因素。结果:随访29-121个月,平均52个月。24例中完全缓解16例(66.7%),部分缓解6例(25.0%),总缓解率91.7%。5年生存率58.3%,平均总生存期68个月;肿瘤无进展为61个月。I/II期和III/IV期的平均总生存期分别93个月和42个月(P〈0.01);肿瘤无进展期分别78个月和38个月(P〈0.01);残余肿瘤直径≥2厘米和〈2厘米的平均总生存期分别为32个月和88个月,肿瘤无进展期分别23个月和82个月(P〈0.01)。结论:满意的肿瘤细胞减灭术后辅以紫杉醇和卡铂化疗能延长患者生存期。
作者 何爱琴
出处 《交通医学》 2010年第6期692-693,共2页 Medical Journal of Communications
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参考文献6

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