摘要
目的观察以疏肝健脾法组方的消渴安胶囊治疗葡萄糖耐量减低(impaired glucose tolerance,IGT)患者的疗效。方法 167例IGT患者被随机分为治疗组83例及对照组84例。治疗组口服消渴安胶囊,对照组口服阿卡波糖片,疗程均为6个月。治疗1个疗程后进行疗效评定及相关检查资料的统计分析。结果与治疗前相比,两组患者治疗后空腹血糖(FPG)及餐后2h血糖(2hPG)、空腹胰岛素含量(FINS)及餐后2h胰岛素含量(2hINS)、空腹C肽(FC-P)含量及餐后2h C肽(2hC-P)含量、三酰甘油(TG)和HOMA-IR等指标均明显降低(P<0.05,P<0.01);与对照组治疗后相比,治疗组上述指标差异无统计学意义(P>0.05)。结论中药消渴安胶囊治疗IGT疗效显著,能较好的预防2型糖尿病的发生,其疗效与阿卡波糖具有可比性,值得推广。
Objective To observe the effect of Xiaokean capsule which was composed according to the method of soothing the liver and fortifying the spleen on impaired glucose tolerance（IGT）.Methods One hundred and sixty seven patients with IGT were randomly divided into the treated group（83 cases）and the control group（84 cases）.Patients in the treated group were given Xiaokean capsule orally while patients in the control group were administered Acarbose tablet.The effects were evaluated after the treatment for six months.Results After the treatment,FPG,2hPG,FINS,2hINS,FC-P,2hC-P,TG and HOMA-IR in both the treated group and the control group were improved significantly（P0.05,P0.01）.The above parameters in the treated group were not obviously different from the control group either before or after the treatment.Conclusion Xiaokean capsule is effective on treating IGT and delaying the onset of type 2 diabetes.The efficacy of Xiaokean capsule is comparable to Acarbose tablet.
出处
《中西医结合研究》
2010年第6期284-287,共4页
Research of Integrated Traditional Chinese and Western Medicine
关键词
疏肝健脾
消渴安
葡萄糖耐量减低
中医药
soothing the liver and fortifying the spleen
Xiaokean capsule
impaired glucose tolerance
traditional Chinese medicine
