摘要
目的 探讨术前减黄对低位胆道恶性梗阻性黄疽患者行胰十二指肠切除术的影响.方法 对78例行胰十二指肠切除术的低位胆道恶性梗阻性黄疸患者进行回顾性分析.结果 术前减黄组入院时总胆红素为（268±70）μmol/L,至术前下降为（174±55）μmol/L,与减黄前比较差异有统计学意义（P〈0.05）,与未减黄组术前总胆红素[（248±85）μmol/L]比较差异有统计学意义（P〈0.05）;术后并发症发生率为40%（31/78）,其中减黄组为46%（11/24）,未减黄组37%（20/54）,两组比较差异无统计学意义（P〉0.05）,单个并发症发生率两组之间差异亦无统计学意义.结论 术前减黄可以有效降低血清胆红素水平;但术前减黄不能降低低位恶性胆道梗阻患者行胰十二指肠切除术后的病死率和并发症.
Objective To investigate the influence of preoperative biliary drainage on the efficacy of pancreaticoduodenectomy performed in patients with malignant obstructive jaundice. Methods The clinical data about 78 patients with malignant obstructive jaundice were retrospectively analyzed. Resuits The total bilirubin in the biliary drainage group was significantly reduced from （268 ± 70） ~mol/L on admission to（ 174 ± 55 ） μmol/L before the operation,significantly lower than （248 ± 85 ） μmol/L in the non - biliary drainage group before the operation （ P 〈 0.05 ）. Thirty - one patients developed complications,accounting for 40% of the cohort（31/78）. The complication rate was 46% （11/24） in the biliary drainage group and 37% （20/54）in the non -biliary drainage group and there was no significance differ- ence between the two groups （ P 〉 0.05 ）. Conclusion Preoperative biliary drainage can reduce the total bilirubin level. However, it cannot lower the development of complications in patients with malignant obstructive jaundice after pancreaticoduodenectomy.
出处
《临床外科杂志》
2010年第7期449-450,共2页
Journal of Clinical Surgery
关键词
梗阻性黄疸
胆道引流
胰十二指肠切除术
obstructive jaundice
biliary drainage
pancreaticoduodenectomy
