摘要
【目的】了解糖耐量异常（IGT）者颈动脉内膜中层厚度（IMT）与臂踝脉搏波传导速度（baPWV）的变化，并探讨两者的关系。【方法】收集健康体检者中糖耐量异常者81例、2型糖尿病患者78例、糖耐量正常者89例，每例均采用超声检测颈动脉IMT及全自动动脉硬化仪测定baPWV。【结果】随着糖代谢异常的加重，颈动脉IMT逐渐增厚，baPwV逐渐升高（P〈0．05）；单因素相关分析提示IMT、baPWV与年龄、总胆固醇（TC）、甘油三酯（TG）呈正相关；多元回归分析显示年龄是IMT、baPWV的独立危险因素。【结论】早期动脉粥样硬化在IGT阶段就已开始，对糖尿病高危人群应尽早筛查，并应及时采取相应的干预措施。
[Objective]To investigate the relationship between the carotid intimal-medial thickness（IMT） and the brachiat-ankle pulse wave velocity（baPWV） in patients with impaired glucose tolerance（IGT）. [Methods]The IMT and baPWV in 81 patients with IGT, 78 with diabetes and 89 with normal glucose tolerance were detected by using automatic atherosclerosis assay instrument and echography, respectively. [Resutts] With the worsening of abnormal glucose metabolism, both the carotid IMT and baPWV increased gradually（ P 〈0.05）. Univariate analysis revealed that IMT and baPWV were positively related with age, TC and TG. Multifactor regression analysis revealed that age was an independent risk factor of IMT and baPWV, [Conclusion]Early atherosclerosis begins in the period of IGT. For the population with high risk of diabetes, some corresponding intervention measures should be taken in time.
出处
《医学临床研究》
CAS
2010年第12期2199-2201,共3页
Journal of Clinical Research
基金
2008年湖南省保健专项资金科研课题重点项目（A2008-03）
关键词
葡糖耐受不良
颈动脉
臂
踝
glucose intolerance
carotid arteries
arm
angkle
