摘要
目的了解进展期胃、大肠癌手术前后腹腔穿刺滴注化疗对防治复发和肝转移的价值及此方法的可行性。方法选择进展期胃、大肠癌门7例，分别随机归入腹腔穿刺滴入化疗组74例，静脉化疗组53例。二组药物、剂量、应用周期相同.前组手术前后直接腹腔穿刺滴入化疗，后组于手术后周围静脉化疗。结果腹腔滴注化疗组术后2年“无瘤”生存率、复发转移率与静脉组比较具有显著差异（P＜0．05）。两组未见化疗开发症。结论手术前后腹腔滴注化疗对防治进展期胃、大肠癌术后2年复发转移有显著疗效，能有效改善术后2年生存质量，且方法简单、易行、安全、实用。
To study the effect of abdominal parecentesis drip chemotherapy (APDC) before and after operahon of advanced gastric and large interstine carcinoma (AGLIC) on preventing relapse and hepatometastasis as well as the practicablity of this method Methde One hundred and twenty seven patients with AGLIC were selected, and randomly divided into APDC'S(n = 74) and vein chemotherapy's groups(n = 53).The drugr, dosages and using peried of the 2 groups were similar . The former were directly given the APDC before and after operaions and the later done the peripheral vein chemotherapies after operahons. Results After operations, there were significant dtherence in the rate of hath the 2-year'non-tumor' survival and relapse metastasis between the 2 groups after operations(P＜0 .05 ). No chemtherapy's comlications developed in hoth the 2 groups. Conclnsion The APDC before and after operation has abvious effect on preventing relapse and rnetastasis during the 2 years afer the AGLIC operations, can effectively improve the existence quality, and is simple,safe and practical.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1999年第6期453-454,共2页
Cancer Research on Prevention and Treatment
关键词
胃癌
大肠癌
围手术期
腹腔滴注化疗
药物疗法
Rectal carcinoma
Carcinoma of colon
Gastric carcinoma
Pharmacotherapy
Abdominal cavity
Relapse Metastasis
