摘要
采用光镜形态学观察结合免疫组化染色法，对５ 例颅内卵黄囊瘤标本进行病理学观察。结果显示：颅内卵黄囊瘤典型结构为疏松网状结构区和实性细胞团块区共同存在，并可见Ｓｃｈｉｌｌｅｒ 小体和玻璃样小体。ＡＦＰ 阳性５ 例，ＰＬＡＰ 阳性３ 例，ＳＰ１ 阳性３ 例，ＨＣＧ、ＣＥＡ、ＣＫ、ＥＲ 全部阴性。提示：颅内卵黄囊瘤常伴有畸胎瘤和生殖细胞瘤成分存在，其形态学、发生学及免疫组化特点均与生殖腺卵黄囊瘤无明显差异。
cases ofintracranial yolk sac tumors were researched and compared from testis yolk sac tumors. Morphological and im munohistochemical stain feature was observed with light microscopy . Microscopically there was a characteristic pattern with Schiller Dural bodies, vacuolated network and solid nodular areas . Hyaline globules were also observed . With theim munoperioxidase technique ,5 cases AFP positive ,3 cases PLAP positive and 3 cases SP1 positive could be located in the tumor cells. HCG was all negative in 5 cases. Intracranial yolk sac tumor was frequently mixed with teratoma and germinoma . There was no observable difference between intracranial yolk sac tumor from testis yolk sac tumor, wherever morphologicalfeature and im munohistochemicalcharacterization .
出处
《首都医科大学学报》
CAS
1999年第4期279-281,共3页
Journal of Capital Medical University
关键词
颅内肿瘤
卵黄囊瘤
免疫组织化学
intracranialtumor
yolk sac tumor
im munohistochemistry
