摘要
目的：探讨局部用减充血剂对鼻粘膜血管运动调控的影响，为研究和防治药物性鼻炎提供理论依据。方法：调查92例急、慢性鼻炎患者分别使用4种不同减充血剂后鼻塞变化的情况；并通过前鼻测压法观察部分患者用药后鼻阻力的反弹现象。结果：4组被调查者中分别有63．5％，31．2％，32．2％，8．6％的患者出现鼻塞反弹性加重；3组被检测者中分别有50％，20％和75％出现鼻阻力反弹性升高。结论：局部用减充血剂可以引起鼻阻力的反弹性升高，其发生率与患者的病情及使用的药物有关；调控鼻粘膜血管运动的舒血管机制被激活，可能是其产生的机理。
Objective:To investigate the effect of decongestant on nasal resistance so as to provide theoriesfor studing rhinitis medicamentosa. Method:The changes of nasal blockage in 92 cases of acute rhinitis and chro-nic rhinitis after using decongestants were recorded, and the nasal resistance in 39 cases were measured by activeanterior rhinomanometry. Result: According to the diseases and decongestents used, the percentage of nasal resis-tance rebound were 63. 5%,31. 2 %, 32. 2%, 8. 6% in 4 groups of investopted patients and 50%,20%,75 % in3 groups of measured patients respectively. Couclusion:Decongestants can cause the rebound of nasal resistance,which relates to the diseases and the decongestants used. The mechasm may be that the factors dilating thevasa in nasal mucosa are activated.
出处
《临床耳鼻咽喉科杂志》
CSCD
1999年第12期560-561,共2页
Journal of Clinical Otorhinolaryngology
关键词
鼻血管收缩药
鼻阻力
鼻炎
鼻堵塞
Nasal vasoconstrictor agents Nasal resistance Rhthetis Nasal obsxtruction
