摘要
观察了该药对轻、中度癌痛的治疗作用 ,并从现代医学角度探讨了作用机制。临床研究表明 :单纯以癌痛欣滴鼻剂治疗轻、中度癌痛患者 41例 ,首次用药后 60 min内 ,中度 ( 级 )以上疼痛缓解率为 73.13% ,总有效率为 92 .68% ,平均起效时间 4.2 0± 1.13min,且无明显不良反应。动物实验表明 :癌痛欣滴鼻剂具有良好的镇痛作用 ,能提高大鼠下丘脑中 β-内啡肽含量 ,并能明显抑制 S180 小鼠局部肿瘤的生长 ,延长荷瘤小鼠生存期 ,促进免疫器官增生。
The therapeutic action of Aitongxin nose drops against pain in light or moderate degree in cancer patients was observed,and its mechanism was studied at the angle of morden medicine. Forty one cases were treated only with the drug.In 60 minutes after the first dose,the lysis rate of pain in grades 2 to 4 was 73.17% and the total effective rate was 92.68%,the mean time of initiatory effect was (4.20±1.13)min.The experimental study showed that the naristillae can relieve pain excellently,and improve the level of β EP in hypothalamus.Moreover,it can prolong the life of tumor bearing mice,restrain the growth of local tumor and improve proliferation of immune organs.
出处
《山东中医药大学学报》
1999年第6期430-433,共4页
Journal of Shandong University of Traditional Chinese Medicine
关键词
癌痛
癌痛欣滴鼻剂
实验研究
中医药疗法
Cancer pain Aitongxin nose drops Clinical and experimental study
