摘要
1例61a男性患者,因肺小细胞癌入院之前行EP(顺铂、足叶乙甙)方案化疗7个疗程,并予多次放射性治疗,治疗过程中无口腔溃疡发生。入院后给予VCM方案(甲氨蝶呤40mg、环磷酰胺1.6g、长春新碱4mg)化疗,并于化疗前始给予腺苷钴胺片、碳酸氢钠片口服。2d后患者出现咽痛及舌尖疼痛,7d后口腔溃疡逐渐加重,致使化疗中断,给予碘甘油、呋喃西林溶液、重组人表皮生长因子外用溶液(Ⅰ)、康复新液、苯扎氯铵溶液外用,20d后痊愈。
A 61-year-old male patient who was diagnosed as small cell lung cancer received EP chemotherapy regimen（cisplatin and etoposide） for 7 cycles and radiation therapy before admission.During that treatment period,the patient had no symptom of oral ulcer.Chemotherapy regimen of VCM（methotrexate 40 mg,cyclophosphamide 1.6 g and vincristine 4 mg） was applied after admission in our hospital.The cobamamide and sodium bicarbonate tablets were given before the treatment with VCM regimen.He developed sore throat and tongue pain after two days,and the symptom aggravated after 7 days,then the chemotherapy was stopped.Iodine glycerine,furacilin solution,recombinant human epidermal growth factor for external use,Kangfuxin liquid and benzalkonium chloride solution were given for external application.The patient recovered from oral ulcer after 20 days.
出处
《中国药物应用与监测》
CAS
2010年第6期386-387,共2页
Chinese Journal of Drug Application and Monitoring
关键词
肺癌
化疗
口腔溃疡
Lung cancer
Chemotherapy
Oral ulcer
