摘要
对丁卡因在玻碳电极上的伏安行为进行了研究,发现在0.1mol/L高氯酸溶液中,于1.04V(vs.Ag/AgCl)左右产生一个与丁卡因呈良好线性关系的阳极氧化伏安峰,大多数金属离子和20多种有机生化物质不干扰测定.方法用于注射针剂和加标尿样中丁卡因的测定,结果满意,对电极反应也进行了初步探讨.
The anodic voltammetric behavior of anaesthetic tetracine and its application were studied. In 0.1 mol/L HClO4 solution, the potential of anodic peak for tetracine is 1.04 V(vs. Ag/AgCl) at a glassy carbon electrode. A Lnear relationship between the peak height and the concentration of tetracine in therange of 5×10-4～1×10-1g/L was obtained. The peak current decreases with the decreasing acidity ofthe solution. the mehtod has been used for the direct determination of tetracine in injections. The averagerecoveries of tetracine in urine samples were 98.5% . The mechanism of the electrode reaction was also discussed.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
1999年第10期1156-1159,共4页
Chinese Journal of Analytical Chemistry
关键词
丁卡因
玻碳电极
伏安法
测定
Tetracine, glassy carbon electrode, voltammetry
