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急性上消化道出血规范化治疗与经验性治疗初步对照研究 被引量:26

Comparative Study of the Effects of Symptomatic Treatment and Standardized Treatment on Acute Upper Gastrointestinal Bleeding
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摘要 目的观察急性上消化道出血(AUGIB)患者的规范化诊治流程治疗效果是否优于既往的经验性治疗。方法对31例AUGIB患者进行随机分组,对照组(14例)给予经验性治疗,观察组(17例)按照中国医师协会急诊医师分会提出的《急性上消化道出血急诊诊治专家共识》进行规范治疗。比较两组患者的止血时间、输血量、住院时间、早期再出血发生率及病死率。结果观察组患者的止血时间〔(12.6±4.7)h〕、输血量〔(375±218)ml〕、住院时间〔(7.3±2.0)d〕、早期再出血发生率(5.9%)及病死率(5.9%)均显著低于对照组〔分别为(20.7±7.9)h、(618±303)ml、(9.9±3.2)d、21.4%和21.4%〕,差异有统计学意义(P<0.05)。结论规范治疗在缩短止血时间及住院时间、减少输血量方面较经验治疗存在显著优势,还能减少早期再出血发生率及病死率。 Objective To determine whether standardized treatment is more effective than symptomatic treatment on acute upper gastrointestinal bleeding(AUGIB).Methods 31 patients with AUGIB were randomly divided into control group(n=14,symptomatic treatment) and treatment group(n=17,standardized treatment,performed according to the Coherent Guidelines for AUGIB by Chinese College of Emergency Physicians).Haemostasis time,blood transfusion volume,length of stay in hospital,rate of early-stage rebleeding and mortality rate were compared between the two groups.Results Haemostasis time((12.6±4.7)h),blood transfusion volume((375±218)ml),length of staying in hospital((7.3±2.0)d),rate of early-stage rebleeding(5.9%) and mortality rate(5.9%) of the treatment group were significantly lower than those of control group((20.7±7.9)h,(618±303)ml,(9.9±3.2)d,21.4% and 21.4%,respectively)(P〈0.05).Conclusion This preliminary study indicated that,compared to symptomatic treatment,standardized therapy on AUGIB exhibited significant predominance,which could effectively evaluate the cause and severity of AUGIB and accelerate the procedure of diagnosis and treatment.
出处 《中国全科医学》 CAS CSCD 北大核心 2010年第36期4124-4126,共3页 Chinese General Practice
关键词 急性上消化道出血 经验性治疗 诊治共识 Acute upper gastrointestinal bleeding Symptomatic treatment Coherent guidelines
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参考文献5

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