摘要
从北京某农场选取5 头骨软病乳牛作为试验组,5 头健康乳牛作为对照组,然后进行血常规、血清学检测。结果表明,试验组乳牛血清钙水平呈下降趋势;血清无机磷水平显著下降;血清AKP活性显著升高,其同工酶特征性酶谱中骨带染色变宽变深;血清维生素D3 活性代谢产物(25OHD3 和1 ,25(OH)2D3) 均显著下降;血清骨钙素(BGP) 水平极显著下降。本试验在国内首次采用BGP指标来研究健康乳牛和骨软病乳牛BGP含量的变化,同时研究表明,BGP测定是诊断乳牛骨软病的一个灵敏、有效的方法。
In this test,five osteomalacia cows were divided into the experimental group and five healthy cows were divided into the control group on Beijing Farm.The results showed that the level of serum calcium was reduction.The level of serum inorganic phosphorus decreased obviously.The activity of serum AKP increased.The zymogram of serum AKP isoenzymes showed that the band of bone AKP isoenzymes became wide and dark.The level of serum BGP reduced significantly.The parameter of BGP was used for studying the changes of healthy and osteomalacia cows for the first time in China.The measure of BGP is a sensitive and effective method in diagnosis of osteomalacia.
出处
《畜牧兽医学报》
CAS
CSCD
北大核心
1999年第6期513-518,共6页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金
国家自然科学基金