摘要
目的探讨结肠癌患者术前营养状况对其术后3年生存期的影响。方法收集并分析我院2004年11月～2007年12月196例行结肠癌手术治疗患者的临床资料,对未进行营养支持的患者使用欧洲营养风险筛查2002量表评估其术前营养风险。并按NRS-2002营养评分结果分为A组(潜在营养风险,即总评分<3分),B组(有营养风险组,即总评分≥3分)。术后定期随访患者,得到其3年生存期指标:生存率、局部复发率、肿瘤转移率和死亡率。结果术后3年生存期指标中:生存率A组高于B组,差异有统计学意义(86.9%vs.71.8%,P=0.011);两组局部复发率(4.03%vs.8.33%,P=0.173)、远处转移率(18.55%vs.30.56%,P=0.054)差异无统计学意义,死亡率A组低于B组,差异有统计学意义(12.90%vs.27.78%,P=0.010)。结论术前营养状态是结肠癌患者术后生存期的影响因素,术前存在营养不良的患者其预后较差,提示结肠癌治疗过程中应注意纠正术前营养不良状况。
Objective To study the impact of preoperative nutrition on 3-year survival of colon cancer patients after surgery. Method Clinical data of 196 colon cancer patients receiving the treatment of surgery in our hospital from November, 2004 to December, 2007 were assessed by preoperative score of nutrition status by Nutrition Risk Screening 2002 （NRS-2002） without nutrition support. According to NRS-2002 preoperative score, the patients were randomly divided into group A （potential preoperative nutritional risk, overall grade〈3） and group B （preoperative nutritional risk needing nutritional support, overall grade≥3 ）, We followed up patients regularly to achieve the index of 3-year survival after surgery, including survival rate, local recurrence rate, tumor metastasis rate and mortality. Result There was 124 cases in group A and 72 cases in group B. Comparing with the index of the 3-year survival after surgery and survival rates between the two groups, group A （86. 9%） was higher than group B （71.8%）, there was significant difference between the two groups （P=0. 011）. Local recurrence rate in group A （4.03%） was the same as in group B （8.33%） （P=0. 173）. the metastasis rate in group A （18. 55%） and group B （30.56 % ） was not significant difference（P〉0.05）, the mortality in group A （12.90 % ） was significant lower than that in group B （27.780%） （p= 0. 010）. Conclusion The preoperative nutritional status affects the 3-year survival of colon cancer patients after Surgery. The preoperative malnourished patient has a serious prognosis. So it suggests that preoperative nutritional status rectification is important in treatment of colon cancer.
出处
《护士进修杂志》
北大核心
2011年第3期197-200,共4页
Journal of Nurses Training
基金
四川省卫生厅科研课题(编号:080271)
