摘要
目的 了解急性白血病 （ Ａ Ｌ） 患儿的肝功能状态。方法 采用比色法测定血清总胆汁酸 （ Ｔ Ｂ Ａ） 和亮氨酸氨肽酶 （ Ｌ Ａ Ｐ） 水平。结果 Ａ Ｌ患儿 Ｔ Ｂ Ａ 水平升高 （ Ｐ ＜ ００５）， 且与外周血白细胞总数成正相关关系 （ｒ＝ ０６１３， Ｐ ＜ ００１）， 升高程度与其 Ｆ Ｂ Ａ 分型无关。 Ｌ Ａ Ｐ水平无明显变化 （ Ｐ ＞ ００５）。结论 Ａ Ｌ患儿存在一定程度肝功能异常， 血清 Ｔ Ｂ Ａ 是检测的敏感指标， 可为实施化疗提供参考。
Objective To investigate the situation of liver function of children with acute leukemia Methods Colorimetric analysis was used to detect serum total bile acids (TBA) and leucine aminopeptidase (LAP) Results Children with acute leukemia had a significant difference statistically from control groups in TBA (P<0 05),but no significantly variation in LAP (P>0 05) The difference of TBA level was not found between the group with acute lymphatic leukemia and the group with acute non-lymphatic leukemia (P>0 05) too TBA level of children with acute leukemia correlated strongly with the total amount of Blood WBC Conclusion The results suggest that abnormal liver functions exist in children with acute leukemia, and the detection of serum TBA is a good method for assessing their liver functions
出处
《蛇志》
1999年第3期36-37,共2页
Journal of Snake
关键词
急性白血病
肝功能
血清
总胆汁酸
亮氨酸氨肽酶
acute leukemia, liver function, serum total bile acids, leucine aminopeptidase
