摘要
目的 研究血管迷走性晕厥（VVS）10年临床情况.方法 2000-01～2010-07在我院诊治不明原因晕厥或先兆晕厥患者1782例,根据检查年限分为A组（2000-01～2004-12,n=280）和B组（2005-01～2010-07,n=1502）,根据年龄分为儿童组（〈18岁,n=1180,男450例,女730例）和成人组（≥18岁,n=602,男182例,女420例）.儿童组平均年龄（9.77±3.92）岁,按照年龄段分为4～6岁、7～10岁和11～18岁三个年龄段;成人组平均年龄（40.78±14.05）岁.结果 ①HUTT阳性率：HUTT总阳性率47.7%,其中儿童组和成人组分别为44.3%和54.3%;在儿童和成人中B组较A组均增加（45.7% vs33.3%,61.4% vs33.1%,P〈0.05）.②HUTT阳性率性别比例变化：儿童组和成人组女性均高于男性（32.2% vs12.1%,42.7% vs11.6%,P〈0.05）;在儿童和成人中B组男性和女性均高于A组（分别为12.5% vs9.3%、33.2% vs24.0%,9.8% vs7.3%、51.7% vs25.8%,P〈0.05）.③HUTT反应类型变化：儿童组和成人组血管抑制型〉混合型〉心脏抑制型（P〈0.05）,其中儿童组血管抑制型B组高于A组（33.8% vs19.4%,P〈0.05）;成人组血管抑制型和混合型B组均高于A组（40.1% vs20.5%,18.4% vs9.9%,P〈0.05）.④儿童组HUTT阳性率年龄变化：儿童组11～18岁组〉7～10岁组〉4～6岁组（P〈0.05）.在各年龄段中,4～6岁及11～18岁B组均高于A组（6.2% vs3.9%,23.3% vs21.7%,P〉0.05）,7～10岁组中B组明显高于A组（16.2% vs7.8%,P〈0.05）.结论 VVS患者的阳性率、反应类型在近10年不断发生变化,提示VVS的发生受社会因素、精神因素、生活方式等多种因素的影响.
Objective To study the changes in the patients with vasovagal syncope （VVS） over ten years. Methods 2000 - 01 - 2010 - 07, 1782 patients with unexplained syncope or prodromata were enrolled in this study and were divided into two groups, A group （2000 -01 -2004 - 12, n = 280） and B group （2005 -01 -2010 -07, n = 1502） ;and were divided into two groups according to the age, children group （ 〈 18 years old, n = 1180,450 males,730 females, mean （ 9.77±3.92 ） years old ] and adults group[ ≥18 years old, n = 602,182 males,420 females, mean（40.78 ±14.05） years old3. Child patients were divided into three subgroups： 4 -6 years old,7 - 10 years old and 11 - 18 years old. Head -up tilt table test （HUTT） was performed in all the subjects and the VVS was diagnosed if the result was positive. Results （1）The total positive ratio of VVS was 47.7%, and the ratio in children and adults was 44.3% and 54.3% respectively; Compared with A group, the ratio in B group was significant higher in children and adults（45.7% vs 33.3% ,61.4% vs 33. t% ,P 〈0.05）. （2）The positive ratio of VVS in female children and adults was significant higher than that of male children and adults （32.2% vs 12.1% ,42.7% vs 11.6%, P 〈0. 05 ） ; Compared with A group, the ratio of males and females in B group was obviously higher among children and adults（ 12.5% vs 9.3% ,33.2% vs 24.0% ;9.8% vs 7.3% ,51.7% vs 25.8% ,P 〈0.05）. （3）In children and adults, the vasodepressor response type hold the highest ratio in VVS（ P 〈 0.05 ）, and the eardioinhibitory response type hold the lowest ratio （P 〈0.05 ） ; Compared with A group, the ratio of the vasodepressor response type in B group was obviously higher among children and aduhs（33, 8% vs 19.4% ,40.1% vs 20.5%, P 〈 0.05 ） ; Compared with A group, the ratio of the mixed response type in B group was obviously higher in adults （18.4% vs 9.9% ,P 〈0.05）. @In the children, the positive ratio of VVS in 11 -18 years was higher than that in 7 -10 years and 4 - 6 years （ P 〈 0.05 ） ; Compared with A group, the ratio of 4 - 6 years and 11 - 18 years in B group was higher（6.2% vs 3.9% ,23.3% vs 21.7% ,P 〉0.05 ） ;Compared with A group, the ratio of 7-10 years in B group was obviously higher（ 16.2% vs 7.8%, P 〈 0.05 ）. Conclusion VVS in positive rate and response type has changed over ten years, and the changes show that VVS is related to social factors, mental factors, life style and so on.
出处
《中国急救医学》
CAS
CSCD
北大核心
2011年第1期25-28,共4页
Chinese Journal of Critical Care Medicine
基金
湖南省科技厅资助项目（No.2008SK3111）
