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心肌梗死患者凝血酶激活纤溶抑制物与纤维蛋白原的关系研究 被引量:3

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摘要 目的探讨心肌梗死患者血浆中凝血酶激活纤溶抑制物(TAFI)的浓度和活性与纤维蛋白原(Fbg)的关系。方法选择心肌梗死患者34例和30例正常人,用ELISA方法和发色底物法分别检测TAFI的抗原(TAFIAg)及活性(TAFIa),与正常人的参考值进行对照分析。结果心肌梗死组TAFIa、TAFI Ag、Fbg均较对照组显著增高。结论心肌梗死患者血浆中TAFIAg、TAFIa均显著增高,TAFI抑制了Fbg的降解,具有抑制纤溶的作用,可能是心肌梗死的危险因子。
出处 《实用心脑肺血管病杂志》 2011年第1期83-83,共1页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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参考文献3

  • 1崔桂萍,杨萍,胡静仪,王颖,姚智.脑卒中患者血浆凝血酶激活的纤溶抑制物的临床研究[J].检验医学,2009,24(1):1-4. 被引量:4
  • 2Leurs J, Hendrlks D. CarboxyupetidaseU (TAFIa) A metallocarboxypeptidase with a distinct role in haemostasis and a possible rlskfactor [ J]. Jthromb Haemost, 2005, 94:471 -487.
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二级参考文献5

  • 1Bajzar L, Manuel R, Nesheim ME. Purification and characterization of TAF I, a thrombin activable fibrinolysis inhibitor [ J ]. Biol Chem, 1995, 270 ( 24 ) : 14477 - 14484.
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