摘要
目的 定量评价肺癌和肺癌远处转移患者前列环素(PGI2)和血栓素A2(TXA2)水平,为肺癌转移提供诊断、鉴别诊断的依据。方法 采用放射免疫测定技术对原发性肺癌未手术组的6例远处转移,8例肺门转移,7例无转移的患者,肺癌行根治术组的6例出现远处转移,7例出现肺门转移,6例未出现转移的患者进行血浆前列环素和血栓素A2检测。结果 原发性肺癌未手术组和行根治术组,无论是远处转移或肺门转移,其PGI2/TXA2比值均明显低于肺癌无转移患者,P<0.05。但肺癌合并远处转移的患者,PGI2/TXA2比值低于肺癌合并肺门转移的患者,P>0.05。结论 PGI2/TXA2比值对肺癌转移的诊断有重要价值。
Objective To explore the PGI 2 and TXA 2 for lung cancer patients and ones with lung cancer metastasis,in onder to provide nomal index for diagnosis and differential diagnosis in lung cancer metastasis.Methods To test plasma PGI 2 and TXA 2 by means of RIA in all cases.One group of patients who received non operative treatment:Six cases of patients with distant metastasis;Eight cases with hilus of long metastasis;Seven cases without metastasis.The other group of patients who received radical operation;Six cases of patients with distant metastasis;Seven cases with hilus of lung metastasis;Six cases without metastasis.Result The PGI 2/TXA 2 ratio of the patient whether distant metastasis or hilus of lung metastasis was obviously lower than that of the patients without metastasis( P <0 05).Conclusion The PGI 2/TXA 2 ratio is of great importance to making diagnosis of lung cancer metastasis.
出处
《临床外科杂志》
1999年第5期269-271,共3页
Journal of Clinical Surgery
