摘要
5-氯磺酰异酞酰氯是合成聚酰胺类反渗透膜、纳滤膜的重要功能单体.采用以3,5-二羧基苯磺酸钠为原料,五氯化磷为氯化剂,制备5-氯磺酰异酞酰氯(CSIC),最佳收率可达71.4%.通过对反应温度、反应时间和反应底物配比等影响因素的研究发现:常压下反应温度应控制在170～180℃;反应时间12.5 h后,结束反应;反应底物配比n(五氯化磷)∶n(3,5-二羧基苯磺酸钠)<1∶1,则收率很低.随着n(五氯化磷)∶n(3,5-二羧基苯磺酸钠)增大,收率增高,当n(五氯化磷)∶n(3,5-二羧基苯磺酸钠)>2.5∶1后,其增大对产品收率影响不大.
5-chlorosulfonylisophthaloyl chloride（CSIC） was an important functional monomer for the synthesis of polyamide reverse osmosis and nanofiltration membrane. Phosphorus pentaehloride （PC15） was used as earbonyl chlorinating agent to prepare 5-chlorosulfonylisophthaloyl ehloride（CSIC） from Sodium 3,5-dicarhoxybenzenesulfonate, and the top yield of CSIC was 71.4%. Effects of reaction conditions such as the reaction temperature, reaction time and the response ratio on the product yield were discussed： at atmospheric pressure the reaction nearly completed after 12.5 hours while the temperature maintained at 170--180℃; If the mole ratio of PCl;to Sodium 3, 5-dicarboxybenzenesulfonate was less than 1 ： 1, few products could be obtained. When the ratio was between 1 ： 1 and 2.5 ： 1, the yield is enhanced by the ratio. As mole ratio is higher than 2.5 ： 1, the yield is hardly affected.
出处
《浙江工业大学学报》
CAS
北大核心
2010年第6期602-604,共3页
Journal of Zhejiang University of Technology
基金
863国家高技术研究发展计划资助项目(2007AA030302)
973国家重点基础研究发展规划项目(2009CB623402)
关键词
5-氯磺酰异酞酰氯
3
5-二羧基苯磺酸钠
五氯化磷
5-chlorosulfonylisophthaloyl chloride
sodium 3, 5-dicarboxybenzenesulfonate
phosphoruspentachloride
