摘要
以紫薯为原料,12周龄雄性原发性高血压大鼠(SHR)和Wistar大鼠为受试动物,研究紫薯全粉、滤渣、淀粉、水溶性提取物的降血压作用。上述分别以低、中、高3个剂量(0.1、1、5g/kgbw)灌胃SHR大鼠和Wistar大鼠,观察对大鼠血压的影响。结果表明:在所选定的灌胃剂量范围内紫薯各成分对正常大鼠(Wistar大鼠)血压无影响。除淀粉外,其他各成分对SHR大鼠的血压均具有显著降低的作用,其中以水溶性提取物作用最为明显,灌胃后,低剂量组在1h时达到最低值,下降了20.83mmHg,中剂量组在2h时达到最低值,下降了23.50mmHg,高剂量组在4h时达到最低值,下降了24.48mmHg,然后血压开始慢慢回升,在8h时基本恢复到灌胃前的水平。提取紫薯淀粉后的副产物均有明显降血压作用。
Purple potato homogenate was filtrated through multiple layers of gauze,and both the filtrate and residue were harvested.After a period of time of sedimentation,the filtrate was separated into two layers,namely water-soluble upper layer and starch-rich lower layer.The effects of purple potato homogenate,its filtration residue and the water soluble and starch-rich factions of its filtrate on blood pressure of spontaneously hypertensive rats （SHR） was investigated by using 12-week-old male SHR and Wistar rats as the trial animals with different gavage administration doses （0.1,1 g/kg bw and 5 g/kg bw）.The results showed that none of the above four materials had an obvious effect on the blood pressure of normal Wister rats in the given dose range.Except the starch-rich fraction,all the others had a significant effect on decreasing blood pressure of SHR.The water-soluble fraction was the most effective antihyperglycemic factor with 20.83 mmHg drop at 1 hour after administration at 0.1 g/kg bw,23.50 mmHg at 2 hours after administration at 1 g/kg bw,24.48 mmHg at 4 hours after administration at 5 g/kg bw.These drops were followed by a slow rebound up to the pre-administration level at 8 hours.From these results,it can be concluded that all the byproducts of purple potato starch extraction have a notable antihyperglycemic effect.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2010年第21期361-364,共4页
Food Science
关键词
紫薯
高血压
原发性高血压大鼠
淀粉
purple potato
hypertension
spontaneously hypertensive rats （SHR）
starch
