摘要
目的:探讨超细大豆皮膳食纤维对正常和四氧嘧啶致糖尿病模型小鼠糖耐量的影响。方法:对正常和四氧嘧啶致糖尿病模型小鼠灌胃5g/kgbw超细大豆皮膳食纤维(140～200目和穿过200目)后进行血糖耐量实验。结果:与正常对照组比较,正常小鼠两个剂量组的血糖曲线下面积分别减小14.94%和15.48%,有显著性差异(P<0.05),餐后血糖峰值分别降低12.38%和12.51%;对糖尿病模型小鼠,两个剂量组的血糖曲线下面积分别减小24.05%和29.68%,有极显著性差异(P<0.01),餐后血糖峰值分别降低38.71%和39.26%。结论:超细大豆皮膳食纤维使正常和糖尿病模型小鼠的糖耐量有显著改善,使餐后血糖峰值及血糖值降低,但大豆皮膳食纤维的粒度差别对正常和糖尿病模型小鼠的血糖耐量和餐后血糖峰值影响差别不明显。
Purpose：To explore the effect of superfine dietary fiber from soybean bran on glucose tolerance in diabetic mice.Methods：Glucose tolerance was determined in common and alloxan-induced diabetic mice fed different granular sizes of superfine dietary fiber （140-200 mesh and more than 200 mesh） at a dosage of 5 g/kg bw each day.Results：Compared with the model group,the areas under the blood sugar curve in common mice treated with superfine dietary fiber at two dosages decreased by 14.94% and 15.48% （P〈0.05）,and blood sugar peaks in common mice after meal at two dosages decreased by 12.38% and 12.51%.Similarly,compared with the model group,the areas under the blood sugar curve in diabetic mice treated with superfine dietary fiber at two dosages decreased by 24.05% and 29.68% （P〈0.01）,and blood sugar peaks in diabetic mice after meal at two dosages decreased by 38.71% and 39.26%.Conclusion：The blood sugar tolerance in common and diabetic mice treated with superfine dietary fiber has an obvious improvement,and blood sugar peaks and blood sugar levels in common and diabetic mice after meal are significantly decreased.However,the granular size of superfine dietary fiber does not exhibit obvious improving effect on blood sugar tolerance and decrease in blood sugar level.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2010年第21期329-331,共3页
Food Science
基金
湖北省自然科学基金项目(2008CDA077)
关键词
超细大豆皮膳食纤维
粒度
糖尿病模型小鼠
糖耐量
superfine dietary fiber from soybean bran
granular size
diabetic mice
blood glucose tolerance
