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N末端脑钠肽在鉴别心源性与非心源性呼吸困难中的临床探讨 被引量:1

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摘要 目的 探讨N末端脑钠肽(NT-proBNP)对心源性及非心源性呼吸困难的临床应用价值.方法 用酶免疫分析法测定104例呼吸困难患者血浆中的NT-proBNP浓度,包括心源性呼吸困难组(CHF组)和非心源性呼吸困难组(非CHF组),观察对比两组患者血浆NT-proBNP的浓度.同时对不同心功能状态左室射血分数(LVEF)及血浆NT-proBNP水平做比较分析.结果 CHF组血浆NT-proBNP浓度明显高于非CHF组,两组差异有统计学意义(P<0.05).CHF组不同心功能分级LVEF及NT-proBNP浓度的比较差异均有统计学意义(P<0.05).NT-proBNP浓度与LVEF呈负相关(r=-0.56,P<0.01).结论 NT-proBNP可作为鉴别心源性及非心源性呼吸困难患者的简便易行的检测指标,值得临床应用.
作者 柴晓利 刘翔
出处 《中国医师杂志》 CAS 2010年第11期1542-1543,共2页 Journal of Chinese Physician
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  • 1史晓敏,林箐,徐国宾,宋以信,夏铁安.血清N末端B型钠尿肽原在心功能评价及慢性充血性心力衰竭诊断中的初步应用[J].中华检验医学杂志,2005,28(1):37-41. 被引量:78
  • 2李镛,顾学章.B-型利钠肽在肺科临床的应用[J].临床肺科杂志,2006,11(2):203-204. 被引量:24
  • 3崔喜梅,卫国红,荆小莉,廖晓星,李欣,熊艳,王西富.N末端脑钠肽对急性呼吸困难的鉴别诊断价值[J].中国急救医学,2007,27(7):601-602. 被引量:26
  • 4[1]Levin ER,Gandner DG,Samson WK.Natriuretic peptides.N Engl J Med,1998,339:321-328.
  • 5[2]Executive summary of the guidelines on the diagnosis and treatment of acute heart failure.The Task Force on Acute Heart Failure of the European Society of Cardiology.Eur Hcart J,2005,26:384-416.
  • 6[3]Morrison KL,Harrison A,Krishuaswamy P,et al.Utility of a rapid B-natriuretic peptide assay in differentiating CHF from lung disease in patients presenting with dyspnea.J Am Coll Cardiol,2002,39:202-209.
  • 7[4]Maisel AS,Krishnaswamy P,Nowak RM,et al.Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure.N Eng J Med,2002,347:161-167.
  • 8[5]Januzzi JL,Kimmenade RV,Lainchbury J,et al.NTproBNP testing for diagnosis and short-term prognosis in acute destabilized heart failure:an international pooled analysis of 1256 patients.The international collaborative of NT-proBNP study.Eur Heart J,2006,27:330-337.
  • 9[6]Harrison A,Morrison LK,Krishnaswamy P,et al.B-type natriuretic peptide predicts future cardiac events in patients presenting to the emergency with dyspnea.Ann Emerg Med,2002,39:131-138.
  • 10[7]Berger R,Huelsman M,Strecker K,et al.B-type natriuretic peptide predicts sudden deaths in patients with chronic heart failure.Circulation,2002,105:595-601.

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  • 1Januzzi JL Jr, Camargo CA, Anwaruddin S,et al. The N-terminal Pro-BNP investigation of dyspnea in the emergency department (PRIDE) study. Am J Cardiol, 2005,95 ( 8 ) : 948-954.
  • 2Cowie MR, Mendez GF. BNP and congestive heart failure. Prog Cardiovasc Dis, 2002,44(4) : 293.
  • 3Hunt SA, Abraham WT, Chin MH, et al. ACC/AHA 2005 Guideline Update for the Diagnosis and Management cff Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on PracticeGuidelines (Writing Committee to Update the 2001 (,uidelines tor the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians andthe international Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation,2005,112 (12) : 154-235.
  • 4Morrison LK, Harrison A, Krishnaswamy P, et al. Utility of a rapid B-natfiuretic peptide assay in differentiating congestive heart failure from lung disease in patients presenting with dyspnea. J Am Coil Cardiol, 2002,39( 2 ) : 202-209.
  • 5Masson S, Vago T, Baldi G, et al. Comparative measurement of N- terminal pro-brain natriuretic peptide and brain natriuretic peptide in ambulatory patients with heart failure. Clin Chem Lab Med, 2002,40( 8 ) : 761-763.
  • 6陈国锋,李子龙,高金丹,汪正权.氨基末端脑利钠肽前体对呼吸困难的鉴别诊断价值研究[J].中国医师杂志,2009,11(4):545-546. 被引量:6
  • 7周晓秋,陈善,余晗,方文雄.脑利钠肽在呼吸困难鉴别诊断中的价值[J].中国基层医药,2009,16(4):661-662. 被引量:2
  • 8李燕,卢彩兰,杨国文,徐姝,陈青,马涛.床旁即时N-末端脑钠肽检测在急性呼吸困难鉴别诊断中的应用价值[J].中西医结合心脑血管病杂志,2009,7(8):974-976. 被引量:2
  • 9盛越锋,王晓锋,范佳,叶宏伟,顾振良,缪韦韦.脑钠肽在急诊呼吸困难患者病因鉴别中的作用[J].中国基层医药,2010,17(22):3097-3098. 被引量:4
  • 10刘树元,王立秋,林朱森,胡媛琴,李天杰.B型利钠肽检测在急诊呼吸困难病因鉴别中应用价值的探讨[J].中国医药,2011,6(2):157-158. 被引量:5

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