摘要
目的:探讨血清中脑钠肽(BNP)与蒽环类药物累积量的相关性。方法:收集使用蒽环类药物化疗后的淋巴瘤患者30例,统计患者所用蒽环类药物的累积量,检测患者血清中的BNP值,分析血清中BNP与蒽环类药物累积量的相关性。结果:蒽环类药物累积量为0～950mg,血清中BNP为5～1276pg/ml,蒽环类药物累积量与血清中BNP无线性相关(P>0.05)。结论:不能推荐使用血清中BNP来检测蒽环类药物心脏毒性累积的严重程度。
Objective：To investigate the serum brain natriuretic peptide（BNP） and the accumulation of anthracyclines relevance.Methods：Use of anthracycline chemotherapy for lymphoma,30 patients,statistics were used anthracycline cumulative amount of test serum BNP values of serum BNP and the accumulation of anthracycline correlation.Results：The accumulation of anthracyclines was 0 to 950 mg,serum BNP was 5 to 1 276 pg/ml,accumulation of anthracyclines and the linear correlation of serum BNP（P0.05）.Conclusion：Serum BNP can not be recommended to detect drugs anthracene ring the severity of the cumulative cardiac toxicity.
出处
《中国当代医药》
2010年第34期32-32,34,共2页
China Modern Medicine
关键词
脑钠肽
蒽环类药物
心力衰竭
充血性
Brain natriuretic peptide
Anthracycline
Heart failure
Congestive
