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辛伐他汀对急性脑梗死患者血清CRP及IL-6水平影响的临床研究 被引量:4

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摘要 目的探讨辛伐他汀对急性脑梗死(ACI)患者血清白细胞介素6(IL-6)及C-反应蛋白(CRP)水平变化的影响。方法将ACI患者54例随机分为辛伐他汀组27例和常规治疗组27例,分别于治疗前及治疗4周后行血清IL-6(放射免疫分析法)及CRP(速率散射比浊法)检测。另选同期健康体检的27例作为对照组。结果 ACI组治疗前血清IL-6,CRP水平均明显高于对照组(均P<0.05)。辛伐他汀组治疗后血清IL-6,CRP水平均明显低于治疗前(均P<0.05),且低于常规治疗组(均P<0.05),差异具有显著性;但仍高于对照组(均P<0.05)。常规治疗组患者治疗后血清IL-6,CRP降低不明显(P>0.05)。结论 ACI患者应用辛伐他汀治疗使IL-6,CRP显著降低,有明显抗炎作用。
作者 吴瑾
出处 《医药论坛杂志》 2010年第21期151-152,共2页 Journal of Medical Forum
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