摘要
目的 探讨急性肾衰患者血清β_２－微球蛋白（βＭＧ）和乳酸脱氢酶（ＬＤＨ）水平的变化及其临床意义。方法 用放射免疫法测定６０例急性肾衰患者少尿期、多尿期、临床治愈期及愈后１个月，血清β-２－ＭＧ和ＬＤＨ含量并与３０例健康人作对照。结果 肾衰患者血清β_２－ＭＧ为１９．６４±３．１８ｍｇ／Ｌ，ＬＤＨ为１０５２．２２±１７５．４７Ｕ／Ｌ，均明显高于健康对照组。结论 急性肾衰患者存在高β_２－ＭＧ和ＬＤＨ，且β_２－ＭＧ和ＬＤＨ与病情轻重和疾病转归密切相关。测定血β_２－ＭＧ和ＬＤＨ可作为判断病情严重程度、预测患者病情发展的客观指标。
Objective To investigate the change and significance in serumβ2-microglobulin (β2- MG ) and lactate dehydrogense(LDH) levels in patients with acute renal failure(ARF). Methods During Oliguria, Polyuria, cure stages and I month after cure in patients with ARF, Serum B2-MGand LDH levels were determined in 60 cases by radioimmunoassay, and 30 healthy served by controls. Results Serum B2-MG and LDH levels were(19.14± 3. 180) mg/l and (1050.22±175.47)u/l respectively in patients with ARF, which were markedly higher than those in normal contrlos. Conclusions High levels of B_2-MG and LDH might be related to the severity of disease in patients with ARF. content of serum B2-MG and LDH can serve as useful parameters to reflect the seventy of disease and predict the prognosis.
出处
《洛阳医专学报》
1999年第1期32-34,共3页
Journal of Luoyang Medical College
