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单磷酸阿糖腺苷联合胸腺肽对乙肝病毒复制标志物作用的研究 被引量:1

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摘要 该文报告选择116例慢乙肝分为3组,单磷酸阿糖腺苷联合胸腺肽治疗组(Ⅰ组)46例,抗乙肝免疫核糖核酸治疗组(Ⅱ组)36例,对照组(Ⅲ组)34例。Ⅰ、Ⅱ、Ⅲ组HBeAg阴转率分别为63.9%,31.3%和16.7%;HBVDNA阴转率分别为56.8%,19.0%和14.3%;抗HBcIgM阴转率分别为56.0%,33.3%和25.9%。显示单磷酸阿糖腺苷联合胸腺肽治疗对乙肝病毒复制有较好的抑制作用,优于Ⅱ、Ⅲ组(P<0.01)。对2例乙、丙型肝炎病毒双重感染,治疗后HBeAg与HBVDNA阴转,丙肝抗HCV与HCVRNA也同时阴转,可能与胸腺肽作用有关。
出处 《中国现代医学杂志》 CAS CSCD 1999年第4期25-25,28,共2页 China Journal of Modern Medicine
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  • 1陈思锋,吴中立.体液和组织磷脂酶A_2简便快速测定法[J].第二军医大学学报,1989,10(3):254-256. 被引量:210
  • 2Takayama K,Qureshi N,Ribi E,et al.Separation and characterization of toxic and nontoxic forms of lipid A.Rev Infect Dis,1984;6:439~443
  • 3Carpati CM,Astiz ME,Rackow EC,et al.Monophosphoryl lipid A attenuates the effects of endotoxic shock in pigs.J Lab Clin Med,1992;119:346
  • 4Astiz ME,Rackow EC,Kim YB.Monophosphoryl lipid A induces tolerance to lethal hemodynamic effects of endotoxin.Circ Shock,1991;33:99
  • 5Astiz ME,Saha DC,Brooks K,et al.Comparison of the induction of endotoxin tolerance in endotoxemia and peritonitis by monophosphoryl lipid A and lipopolysaccharide.Circ Shook,1993;39:194
  • 6Madonna GS,Peterson JE,Ribi EE,et al.Early-phase endotoxin tolerance:induction by a detoxified lipid A derivative,monophosphoryl lipid A.Infect Immun,1986;52(1):6
  • 7Vadas P,Pruzanski W.Role of secretory phospholipase A2 in the pathobiology of disease.Lab Inv,1986;55:391
  • 8Vadas P,Pruzanski W.Induction of group Ⅱ phospholipase A2 expression and pathogenesis the sepsis syndrome.Circ Shock,1993;39:160
  • 9Kellermann W,Frentzel BR,Welte M,et al.Phospholipase A2 in acute lung injury after trauma and sepsis:its relation to the inflammatory mediators PMN-elastase,C3a,and neopterin.Klin Wochenschr,1989;67:190
  • 10Angel J,Berenbaum F,le-Denmat C,et al.Interleukin-induced prostaglandin E2 biosynthesis in human synovial cell involves the activation of cytosolic phospholipase A2 and cytooxgenase-2.Eur J Biochem,1994;226:125

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