摘要
借助MATLAB软件和最优完全子图算法,提取并展示NCBI数据库中烟草脉清病毒完整基因组（NC-003 378.1）上微卫星分布特性。结果表明,计算出了各种1碱-基组~6-碱基组在完整基因组序列上重复出现次数和出现位置,并展示它们的分布规律（指数函数）。烟草脉清病毒完整基因组上各种N-碱基组最大的重复出现次数,随N按指数函数数减少;各种N-碱基组重复出现次数由少到多排序的结果,重复出现次数随序号增加。该研究方法可以系统地运用到其他病毒完整基因组序列微卫星分布特性的提取和展示,从而为有效利用微卫星分布特性研究完整基因组的结构和功能、遗传和变异规律提供依据。
MATLAB software and optimal complete subgraph algorithm were used to extract and reveal the microsatellite distribution features in the complete genomes of the tobacco vein clearing virus（NC-003 378.1） from the NCBI database.The results showed that the repetitions number and their location of the N-base group has been extracted and displayed.The largest repetitions of N-base group in the complete genomes of the tobacco vein clearing virus was decreased as the exponential function with the increasing of N.The method used in this study could be applied to the extraction and revealing of the microsatellite distribution features in the complete genomes of other viruses,thereby provided a basis for the research of the structure and the law of function,inheritance and variation by the using of the microsatellite distribution features.
出处
《安徽农业科学》
CAS
北大核心
2010年第32期18082-18085,共4页
Journal of Anhui Agricultural Sciences
基金
湖北省"十一五"教学科学发展规划项目(2006B131)
关键词
烟草脉清病毒
完整基因组
微卫星
分布特性
最优完全子图算法
Tobacco vein clearing virus
Complete genomes
Microsatellite distribution
Means of genetic algorithms
Optimal complete subgraph algorithm
