摘要
研究现神经纤维向下丘脑前区的投射，为光线通过视觉通路的介导调节昼夜节律的理论提供形态依据。采用霍乱毒素亚单位B标记的辣根过氧化物酶（CB－HRP）顺行追踪技术和免疫组化学技术。结果表明现神经纤维投射到视上核背侧区，投射到下丘脑外测区；血管加压素（VP）样免疫反应神经元见于视上核。提示视神经纤维可能与视上核内的VP样免疫反应神经元有直接联系，视上核可能是下丘脑前区昼夜节律系统的组成部分。
Objective: To investigate the projection of the optic nerve fibers to the hypothalamus and the connection between the optic never fibers and VP-like immunoreactive neuronsof the hypothalamus,it provide the morphologic base for the thesis that the light regulate circadian rhythm by the optic never tracts. Method:The CB-HRP antrograde tracing which ismore sensitive than that of the Free-HRP and the immunocytochemistry tecknique were employed in this study. Results:The optic never fibers projected to the dorsomedial portions ofthe supraoptic nucleus and the lateral portion of the hypothalamus3VP-like immunoreactiveneurons were seen in the supraoptic nucleus. Conclution: The results suggested that opticnever fibers could make directly contact with the VP-like immunoreactive neurons in the dorsomedial portion of the supraoptic nucleus and the supraoptic nucleus would be the portion ofthe circadian rhythm system in the hypothalamus.
出处
《解放军医学高等专科学校学报》
CAS
1999年第1期30-33,共4页
Clinical Journal of Medical Officer
关键词
视上核
视神经
神经传导
昼夜节律
Supraoptic nucleus
Optic Never
CB-HRP Immunocytochemistry
Rat
