摘要
目的:探讨氨茶碱对胎儿宫内发育迟缓的疗效及其机制。方法:随机给予57例IUGR孕妇(观察组)每日静滴氨茶碱0.25g,连续10d;54例IUGR孕妇(对照组)给予维生素C2.0g,静滴10d,两组其余治疗相同。结果:观察组的胎儿双顶径在治疗后两周增长2.25±0.07mm,其新生儿的出生体重为3.25±0.13kg,显著高于对照组。结论:静滴氨茶碱治疗胎儿宫内发育迟缓效果优于维生素C,其作用机制可能是促使子宫胎盘血流量增加,提高母儿间氨基酸的转运能力。
Objective: Effect and its mechanism of aminophyllin on intrauterine growth relaxation (IUGR) were researched.Method: 57 cases of IUGR gravidas (treatment group) were randomly given intravenous aminophyllin 0.25g as infusion daily for 10 days; 54 cases of IUGR gravidas (controlled group) were given intravenous vitamin C 2.0g as infusion daily for 10 days, the remains of treatment were identical in both groups.Results: Fetal biparietal diameter increased by 2.25±0.07mm two weeks after therapy in treatment group, and the weight of neonates at birth were 3.25±0.13kg, being higher significantly than controlled group.Conclusion: The effect of intravenous aminophyllin as infusion in treatment of IUGR is superior to vitamin C, the mechanism of effect may be to promote blood flow increased between uterus and afterbirth and to be increased the transfering capacity of amino acids between mother and foetus.
出处
《中国药师》
CAS
1999年第2期78-79,共2页
China Pharmacist
关键词
宫内发育迟缓
氨茶碱
胎儿
疗效
治疗
Aminophyllin
Fetal biparietal diameter
Weight at birth
Blood flow between uterus and afterbirth
