期刊文献+

内镜套扎术联合善宁治疗食管静脉曲张破裂出血的疗效观察 被引量:1

Medical observation of endoscopic variceal ligation plus Sandostatin in the treatment of esophageal variceal bleeding
暂未订购
导出
摘要 目的观察内镜套扎术(EVL)联合善宁治疗食管静脉曲张破裂出血的疗效。方法 40例患者分为两组,实验组给予EVL+善宁治疗,对照组给予EVL+氨甲苯酸治疗。观察两组患者的72h止血率、1个月再出血率、病死率。结果实验组72h内止血率为95%,1个月内再出血率为10%,死亡率为5%;对照组患者72h止血率为80%,1个月内再出血率为15%,死亡率为10%。两组的72h止血率、1个月再出血率比较,差异均有统计学意义(P<0·05);两组的死亡率比较,差异无统计学意义(P>0·05)。结论 EVL术联合善宁治疗食管静脉曲张出血可有效提高止血率,降低再出血率。 Objective To evaluate the efficacy of endoscopic variceal ligation (EVL) plus Sandostatin in the treatment of acute esophageal vaficeal bleeding in cirrhotic patients.Methods 40 patients with active variceal bleeding under emergency endoscope were assigned to two groups,the experimental group was treated with EVL and Sandostatin,the control group was treated with EVL and Aminomethylbenzoic.The hemostasis rates for 72 hours,one month rebleeding rates and mortality rates were observed.Results In the experimental group,the hemostasis rates for 72 hours,one month rebleeding rates and mortality rates were 95%,10%and 5%;in the control group,the hemostasis rates for 72 hours,one month rebleeding rates and mortality rates were 80%,15% and 10%.The hemostasis rates for 72 hours and one month rebleeding rates in the two groups were compared,the differences were statistically significant(P005);the mortality rates in the two groups were compared,the differences was not statistically significant (P005).Conclusion EVL plus Sandostatin is a more effective way for controlling acute esophageal vafieeal bleeding,which could elevate hemostasis rates and reduce rebleeding rates.
作者 张锦春
出处 《中国现代药物应用》 2010年第22期7-8,共2页 Chinese Journal of Modern Drug Application
关键词 食管静脉曲张破裂出血 内镜套扎术 生长抑素 疗效观察 Esophageal variceal bleeding Endoscopic variceal ligation Sandostatin Efficacy
  • 相关文献

参考文献7

二级参考文献41

  • 1Garcia-Tsao G.Current management of the complications of the cirrhosis and portal hypertension:variceal hemorrhage,ascites and spontaneous bacterial peritonitis.Gastroenterology,2001,120:726-748.
  • 2Rossle M,Siegerstetter V,Olschewski M,et al.How much reduction in portal pressure is necessary to prevent variceal rebleeding? A longitudinal study in 225 patients with transjugular intrahepatic portosystemic shunts.Am J Gastroenterol,2001,96:3379-3383.
  • 3Reynaert H,Thompson MG,Thomas T,et al.Hepatic stellate cells:role in microcirculation and pathophysiology of portal hypertension.Gut,2000,50:571-581.
  • 4Chan CC,Wang SS,Lee FY,et al.Endothelin-1 induces vasoconstriction on portal-systemic collaterals of portal hypertensive rats.Hepatology,2001,33:816-820.
  • 5Garcia-Pagan JC,Villanueva C,Vila MC,et al.Isosorbide mononitrate in the prevention of first variceal bleed in patients who cannot receive beta-blockers.Gastroenterology,2001,121:908-914.
  • 6Bellis L,Berzigotti A,Abraldes JG,et al.Low doses of isosorbide mononitrate attenuate the postprandial increase in portal pressure in patients with Cirrhosis.Hepatology,2003,37:378-384.
  • 7Reynaert H,Vaeyens F,Qin H,et al.Somatostatin suppresess endothelin-l-induced rat hepatic stellate cell contraction via somatostatin receptor subtype 1.Gastroenterology,2001,121:915-930.
  • 8Merkel C,Marin R,Sacerdoti D.Long-term results of a clinical trial of Nadolol with or without Isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis.Hepatology,2000,31:324-329.
  • 9Schepke M,Werner E,Biecker E,et al.Hemodynamic effects of the angiotensin Ⅱ receptor antagonist irbesartan in patients with cirrhosis and portal hypertension.Gastroenterology,2001,121:389-395.
  • 10Escorsell A,Bordas JM,Feu F,et al.Endoscopic assessment of variceal volume and wall tension in cirrhotic patients:effects of pharmacological therapy.Gastroenterology,1997,113:1640-1646.

共引文献96

同被引文献5

引证文献1

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部