摘要
目的评价地尔硫卓对肺心病合并不稳定型心绞痛患者的疗效和安全性。方法选择207名肺心病合并不稳定心绞痛患者,随机分为对照组和观察组,在常规治疗措施基础上,对照组给与硝酸甘油,观察组给予地尔硫卓,观察心绞痛症状、心电图及血压、心率、心肌耗氧指数等变化。结果观察组心绞痛短时间内明显缓解,发作次数减少且持续时间明显缩短;心率、血压及心肌耗氧量指数显著下降;心电图缺血性ST-T有明显改善,临床效果较对照组显著。结论地尔硫卓用于肺心病合并不稳定心绞痛患者有效而且安全。
【Objective】To investigate the clinical efficacy and safety of diltiazem in pulmonary heart disease patients with unstable angina pectoris.【Methods】207 pulmonary heart disease patients with unstable angina pectoris were studied and randomly divided into the control group and observed group.The control group were given nitroglycerin while the observed group were given diltiazem.The changes of angina symptom,electrocardiogram（ECG） and hemodynamics were observed.【Results】Angina symptoms were remarkably relieved after the bolus diltiazem in the observed group,and the onset frequency of angina and the longest duration peronset after administration of diltiazem were significantly decreased.Abnormal S-T segments on ECG obviously improved in the observed group.Heart rate（HR） and blood pressure（BP） were significantly decreased.【Conclusion】Diltiazem therapy is effective and safe for pulmonary heart disease patients with unstable angina pectoris.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2010年第7期1089-1092,共4页
China Journal of Modern Medicine
关键词
地尔硫卓
肺心病
不稳定型心绞痛
diltiazem
pulmonary heart disease
unstable angina pectoris
