摘要
目的 研究伴有胸腺样成分（ｃａｒｃｉｎｏｍａ ｓｈｏｗｉｎｇｔｈｙｍｕｓｌｉｋｅ ｅｌｅｍｅｎｔ，ＣＡＳＴＬＥ） 甲状腺癌的组织发生、形态学和生物学特性，以区别于一般鳞状细胞癌。方法 分析患者的临床资料，包括主要体征、手术记录及生存时间，并复习全部病理切片。结果 伴有ＣＡＳＴＬＥ的甲状腺癌不同于鳞癌，不仅有典型的鳞状分化特点，亦伴有胸腺分化特征，如哈氏小体、淋巴上皮样结构和间质淋巴组织增生；ＣＡＳＴＬＥ的预后较其他鳞癌为佳，本组病例中位生存期为１０．５ 年。结论 重新认识具有ＣＡＳＴＬＥ特征的甲状腺癌。
Objective To report 8 cases of squamous cell carcinoma showing thymus like element (CASTLE) of the thyroid. Methods Clinical data and pathological sections were retrospectively reviewed.Results CASTLE of the thyroid differed from ordinary squamous cell carcinoma (SCC) in that it not only presented typical squamous pattern of differentiation, but also admixed with thymic architecture, such as Hassall′s corpuscles, lymphoepithelial like structure and mature lymphocyte infiltration in the stroma. CASTLE of the thyroid had much better prognosis than that of the ordinary SCC of the thyroid with a median survival time of 10.5 year. Histogenesis of CASTLE was discussed. Conclusion Thyroid CASTLE is of rare occurrence. It should be distinguished from SCC of thyroid in order to treat such patients adequately.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
1999年第4期303-304,共2页
Chinese Journal of Oncology
关键词
甲状腺癌
胸腺样成分
病理学
预后
Thyroid neoplasms/pathology Carcinoma, squamous cell/pathology Prognosis
