摘要
目的探讨抗菌药物合理应用指导原则的临床实践意义,提高合理用药水平和抗感染疗效。方法通过行政干预和宣传教育等措施提高合理用药率和治愈好转率,缩短抗感染疗程。结果干预前病原学送检率、联合用药率、合理或基本合理用药率分别为44.23%、51.44%、63.46%,干预后分别为58.82%、45.80%、75.21%。干预前后治愈好转率提高4.20个百分点(97.48%),平均抗感染疗程缩短0.97d(8.97d),医院感染发生率和药物不良反应发生率下降趋势不明显。结论科学有效的行政管理和宣传教育等干预措施,有助于提高抗菌药物使用合理性和抗感染疗效。
【Objective】To survey the curative effect of the intervention measures according to the guiding principle of antibiotics rational use and raise the rate of the rational use of antibiotics.【Methods】The rational use of antibiotics was applied to shorten the course of treatment by the measure of administration and education.【Results】 The rate of the sample deliver was 44.23 %, the rate of combined use of antibiotics was 51.44 %, the rate of the rational use of antibiotics was 63.46 % before intervention. The rate of the sample deliver was 58.82 %, the rate of combined use of antibiotics was 45.80 %, the rate of the rational use of antibiotics was 75.21 % after intervention. The cure rate was 97.48 % with a rise of 4.20 % and the course of treatment was 8.97 days after intervention. The decline was not markedly different in the rate of nosocomial infections and the rate of drug side effect.【Conclusion】The intervention measure of administration and education can raise the rate of the rational use of antibiotics and cure rate of infections.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2010年第4期581-583,586,共4页
China Journal of Modern Medicine
基金
杭州市科技开发项目(No:20071050)
关键词
细菌
感染
抗菌药物
治疗
bacterium
infection
antibiotics
cure
