摘要
目的:研究大萼香茶菜总二萜对机体免疫功能的调节作用。方法:采用正常及腹腔注射环磷酰胺所致免疫功能低下小鼠模型,观察总二萜对细胞免疫和体液免疫功能的影响。结果:大萼香茶菜总二萜可显著提高正常及免疫低下小鼠的免疫脏器系数、提高血清素水平,并显著增强机体迟发性超敏反应。但大萼香茶茶总二萜对巨噬细胞碳廓清速率无显著影响。结论:大萼香茶茶总二萜具有显著增强小鼠免疫功能的作用。
Objective: The regulatory effects of total diterpene of Rabdosia macrocalyx (Dunn) Hara on immune function were studied. Methods: The experimental immunosuppressive mouse models were induced by injection of cyclophosphamide. Results: The index of thymus gland and spleen in normal and immunosuppressive mice were increased significantly. So were the level of hemolysin in serum when 50 mg/kg total diterpene were given. Delayed hypersensivity were also enhanced at the same condition. But there didn't show any change in carbon clearance test. Conclusion; Total diterpene of Rabdosia macrocalyx (Dunn) Hara possesses obvious regulatory action on immune function in mice.
出处
《中药材》
CAS
CSCD
1999年第7期348-350,共3页
Journal of Chinese Medicinal Materials
关键词
大萼香茶菜
总二萜
细胞免疫
实验研究
Total diterpene of Rabdosis macrocalyx
Cellular immunity
