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C-myc与非霍奇金淋巴瘤的关系研究进展 被引量:3

Research on the relationship between the C-myc and non-Hodgkin,s lymphoma
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摘要 非霍奇金淋巴瘤(NHL)是全球发病率最高的五大肿瘤之一,近年来发病率呈明显上升趋势。原癌基因C-myc在基因转录调控机制中发挥着重要作用,与NHL的发生、发展和演变转归有重要关系。将C-myc基因作为NHL的研究重点,能够使我们对NHL的发病机制有进一步的了解,为NHL分型、预后判断和制定治疗方案等提供可靠的理论依据。 Non-Hodgkin's lymphoma(NHL) is one of the five most common cancer in the world,in recent years,its incidence has clearly been an upward trend.Proto-oncogene C-myc plays an important role in gene regulation mechanism of transcription,closely related to NHL's occurrence,development and evolution.C-myc gene study of NHL can give us a better understanding of pathogenesis,and provide a reliable theoretical basis for the NHL's sub-type,prognosis and the development of treatment programs.
作者 王京琼 孟丹
机构地区 宁波大学医学院
出处 《现代肿瘤医学》 CAS 2010年第12期2489-2491,共3页 Journal of Modern Oncology
基金 宁波市科学技术局资助项目(编号:2005C100118)
关键词 C-MYC 非霍奇金淋巴瘤 基因重排 临床诊断 预后 C-myc Non-Hodgkin's lymphoma rearrangement clinical diagnosis prognosis
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参考文献28

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二级参考文献87

共引文献40

同被引文献35

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