摘要
目的回顾性分析宫颈癌患者血红蛋白(Hgb)水平对根治性放射治疗预后的影响。方法经病理诊断证实宫颈癌患者862例行根治性放射治疗,外照射采用8MV-X射线前后二野或盒式四野照射方法,剂量(30～36)Gy后行宫旁淋巴引流区推量照射(18～24)Gy;宫颈腔内近距离放疗(6～7)Gy/次×(5～6)次;放疗总剂量:A点(60～70)Gy,B点(50～55)Gy。放疗中对症止血治疗。结果不同程度贫血对宫颈癌放疗的局部控制率和远期疗效有明显影响。结论 Hgb浓度影响宫颈癌的局部控制率和远期生存率,放疗前尽量提高患者Hgb水平至100g/L以上。
Objective To investigate the impact of the cervical cancer patients＇hemoglobin（Hgb）level on the prognosis of radical radiotherapy by retrospective analysis.Methods Eight hundred and sixtytwo pathologically verified patients with cervical cancer were treated with radical radiotherapy,8MV-X ray was used for external radiation with a dose of（30～36）Gy by anterior-posterior two-fields or boxlike four-fields radiation technique,and then the lymphatic drainage area beside pelvic was added a dose of（18～24）Gy.Meanwhile,the patients were also treated with after loading radiotherapy with the dose of（6～7）Gy/fraction×5-6 fraction.The total dose of A point is（60～70）Gy,B point is（50～ 55）Gy.During the radiotherapy,we gave the patients symptomatic treatment.Results The anemias in different degree have significant impact on the local control rate and long-term survival rate of the cervical cancer patients who were treated with radiotherapy.Conclusion The concentration of Hgb influences the local control rate and long-term survival rate of cervical cancer patients.We should elevate the patients＇Hgb level higher than 100g/L before radiation.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2010年第11期1300-1302,共3页
Cancer Research on Prevention and Treatment
关键词
宫颈癌
放射治疗
血红蛋白
预后
Cervical cancer
Radiotherapy
Hemoglobin
Prognosis
