摘要
目的:评价玻璃体切除联合曲安奈德(triamcinolone acetonide,TA)球内注射治疗增生性糖尿病视网膜病变(proliferative diabetic refinopathy,PDR)的疗效。方法:分析本院因PDR住院治疗患者90例98眼,玻璃体切除术联合TA球内注射50眼和单纯行玻璃体切除术48眼,比较两组患者治疗前后的矫正视力、眼内炎症、反应眼压和眼底等情况。结果:随访至术后6mo。TA注射组术后前房炎症反应及黄斑水肿的发生率较单纯手术组降低,其差异有统计学意义(P<0.05),术后视力改善程度及眼压升高的发生率组间差异无统计学意义。结论:玻璃体切除联合TA球内注射治疗PDR与单纯玻璃体切除术比较,可以减少术后眼内炎症反应及黄斑水肿的发生。
AIM:To explore the clinical effect of pars plana vitrectomy(PPV)combined triamcinolone acetonide (TA) intravitreal injection for proliferative diabetic retinopathy (PDR).
METHODS:The study included 90 patients with PDR was who underwent PPV: TA group included 50 eyes, control group included 48 eyes. The visual acuity, inflammation, intraocular pressure and fundus were evaluated after surgery.
RESULTS:In the postoperative month 6,the inflammation reaction of anterior chamber and macular edema in TA group was less than that in control group (P〈0.05).But the corrected visual acuity and intraocular pressure showed no shown statistical significance.
CONCLUSION:PPV combined TA intravitreal injection for PDR is useful to reduce postoperative intraocular inflammation and macular edema.
出处
《国际眼科杂志》
CAS
2010年第12期2346-2347,共2页
International Eye Science
基金
中国川北医学院苗圃基金资助项目[苗圃(08)临-16]~~