摘要
乳铁蛋白是一种铁结合性糖蛋白，在牛初乳中含量高达1g/L，是常乳含量的五倍。乳铁蛋白具有抗菌、抗氧化、抗病毒、抗癌症等多种生物学功能，95％纯度的乳铁蛋白每公斤价值1000$。近些年来，乳铁蛋白的分离纯化技术研究达到了较高水平，主要有离子交换色谱法、盐析和凝胶层析法、超滤和离子交换色谱法结合、混合模式扩张床吸附法等，但是能够直接工业化生产的方法还有待于进一步研究和完善。
Lactoferrin is an iron-binding glycoprotein. The content of lactoferrin in bovine colostrum is up tol g/L, which is five times higher than that in the milk. Lactoferrin has many biological functions such as antibacterial, antioxidant, antiviral and antieaneer etc. The value of lactoferrin with a purity of 95% is 1000 dollar per kilogaram. There are many methods for isolation and purification of laetoferrin. In recent years, technologies for lactoferrin separation and purification technology reached a high level. The main methods include ion-exchange chromatography, salting-out and gel chromatography method, ultrafiltration and ion-exchange chromatography and mixed-mode expanded bed adsorption. The methods for direct industrial production will been further studied and improved.
关键词
乳铁蛋白
提取
纯化
工业化生产
Lactoferrin（Lf）
Extract
Purification
Industrialization
