摘要
目的:了解脑梗死并发肺部感染病原菌与抗菌药物使用间的关系。方法:回顾性分析33例脑梗死并发肺部感染病原菌及抗菌药物治疗情况。结果:患者以男性和老年人居多;革兰阴性菌感染占优势(67.9%);产超广谱β-内酰胺酶的肺炎克雷伯菌和大肠埃希菌的检出率为42.9%;铜绿假单胞菌对常用的多种抗菌药物耐药;抗菌药物应用率最高的依次为头孢哌酮/舒巴坦、左氧氟沙星和莫西沙星。结论:分析感染病原菌与抗菌药物应用的关系,可为临床合理用药提供参考。
OBJECTIVE： To investigate the relationship between acute cerebral infarction with pulmonary infection-inducing pathogen and the clinical utilization of antibacterials. METHODS ： 33 cases of acute cerebral infarction with pulmonary infection-inducing pathogen and clinical antibacterial medicine treatment were analyzed retrospectively. RESULTS： Male and aged patients were mainly involved. Gram-negative bacterial infections took predominate place （67.9%）. The detection rate of Klebsiella pneumoniae of ESBLs and Escherichia coli reached 42.9%. Pseudomonas aeruginosa was resistant to many kinds of antibiotics. Cefoperazone/sulbactam, levofloxacin and moxifloxacin were the top 3 drugs in the list of utilization rate. CONCLUSION： This research can provide some references for clinical reasonable use of drug.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第46期4361-4363,共3页
China Pharmacy
关键词
脑梗死
肺部感染
病原菌
抗菌药物
Cerebral infarction
Pulmonary infection
Pathogen
Antibacterials
