摘要
Ｗｉｌｓｏｎ［１］于１９９７年发表了关于ＤＮＡ导电性的评论性文章，介绍了各种学派的观点．争论焦点在于ＤＮＡ是否为导体．将两种配合物键合于ＤＮＡ作为接头，通过研究电子转移可确定ＤＮＡ是否为导线，其中配合物和ＤＮＡ键合模式是研究的关键．Ｂａｒｔｏｎ［２］...
The complexes of \| and \|\{\ \}\+\{2+\}(bpy=2,2\|bipyridine, HPIP=2\|(2\|hydroxyphenyl)imidazo\{\ \}\ phenanthroline) were prepared and their racemic complex were dialysed against calf thymus DNA(CT\|DNA). During the course of dialysis with the solution stirring for 48 h, the CD signals of the dialyzate experience disappearing\|appearing\|disappearing. However, in the similar conditions except for not stirring, strong CD signals appeared. From the results obtained, several novel opinions were suggested. Firstly, the evidence of different binding rates of \| and \|enantiomers of polypyridyl ruthenium() complexes with CT\|DNA, the first example, was demonstrated. As for the dialysis experiment, binding of \|enantiomer is dynamically preferred for CT\|DNA. Secondly, the different binding rates may be deduced from different binding modes of the enantiomers.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1999年第4期525-525,共1页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
广东省基金
关键词
钌配合物
DNA
电子转换
导电性
键合
Ruthenium() complexes, DNA, Enantiomers, CD spectra, Binding rate
