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胰蛋白酶原-2检测对急性胰腺炎的诊断价值 被引量:1

Comparative analysis among trypsinogen- Ⅱ α-amylase and a-amylase for the diagnosis of acute pancreatitis
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摘要 目的探讨胰蛋白酶原-2检测对急性胰腺炎的诊断价值。方法采用免疫层析法测定69例急性胰腺炎(AP)患者尿胰蛋白酶原-2,采用免疫抑制法测定胰腺淀粉酶、酶偶联法测定α-淀粉酶。结果69例AP患者中尿胰蛋白酶原-2阳性65例(94.2%),胰腺淀粉酶阳性63例(91.3%),α-淀粉酶阳性59例(85.5%);尿胰蛋白酶原-2诊断AP敏感性94.2%、特异性90.3%;胰腺淀粉酶诊断AP敏感性91.3%、特异性是87.1%;α-淀粉酶诊断AP敏感性85.5%、特异性74.2%。结论尿胰蛋白酶原-2是诊断AP的较好检测指标。 Objective To discuss the clinic at diagnosis value of trypslnogen-I in acute pancreathis(AP) by the means of comparative analysis among trypsinogen- Ⅱ. p-amylase, and uroamylase. Methods Trypsinogen-1 by immunostratographie analysis, p-Amylase by immuno-suppression and a-Amylase by enzyme couphng reaction. In 69 samples with pancreatitis were measured. Results Trypsinogen- Ⅱ in 65 samplest p-Amylase in 63 samples and Amylase in 59 samples were positive. The diagnositic sensitivity of trypsinogen- Ⅱ , p-Amylase, Amylase were 94.2%, 91.3% and 85.5% ,respectively The diagnositic specificity were 90. 3% ,87. 1% and 74. 2% respectively. Conclusion Trypsinogen- Ⅱis better index for the detection of acute panereatitis.
作者 张凤花
出处 《中国基层医药》 CAS 2010年第21期2957-2958,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 胰腺炎 胰蛋白酶原-2 淀粉酶 Pancreatitis Trypsinogne- Ⅱ Amylase
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