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IL-7及其受体在T淋巴细胞发育中的作用及对运动免疫的意义 被引量：6

The function of interleukin-7/interleukin-7 receptor during T lymphocytes development and the significanee in exercise＇immunity
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摘要 运动训练显著影响机体的免疫功能，T淋巴细胞亚群的平衡是维持免疫系统内部环境稳定的一个中心环节。IL-7／IL-7受体（IL-7R）在促进淋巴细胞，尤其是T淋巴细胞产生、分化和发育成熟的过程中发挥重要作用。从了解IL-7／IL-7R的生物学特性、信号通路及其在T细胞发育、生存、扩增和记忆性T细胞发育中的重要作用，从细胞免疫产生的源头来分析IL-7／IL-7R运动影响免疫功能的机理，可为改善机体免疫功能提供新的思路。 Exercise influences immune tunction significantly. The balance between T lymphocyte subsets is critical importance for the stability of immune system. IL-7/IL-7R are essential for lymphocyte proliferation, development and maturation, especially for T lymphocyte. This paper reviews the biological eharacters of IL-7 and its receptor （IL-7R）. Their importance in the development, peripheral survival, and expansion of Tceils are also summarized.
作者 张琳 郝选明 邓树勋 肖鹏
机构地区 华南师范大学生命科学学院 华南师范大学体育科学学院
出处 《国际免疫学杂志》 CAS 北大核心 2010年第6期442-445,共4页 International Journal of Immunology
基金 广东省自然科学基金（NO：9151063101000059）
关键词 IL-7 IL-7受体 T淋巴细胞发育 运动免疫 Interleukin-7 Interlenkin-7 receptor T lympholeukocyte development Exercise immunity
分类号 R3 [医药卫生—基础医学]
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参考文献19

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同被引文献83

  • 1余婷,杨柱,龙奉玺,吴文宇,王佳,伍谨林,唐东昕.基于网络药理学探讨黄精-百合药对抗癌作用的机制[J].中国实验方剂学杂志,2020,26(5):168-177. 被引量：17
  • 2范翠英,冯利兴,樊金玲,果德安,刘璇.重组蛋白表达系统的研究进展[J].生物技术,2012,22(2):76-80. 被引量：58
  • 3侯云山,乔占兵,尹婷,袁健强.中医学发展回顾与展望[J].中国医药学报,2004,19(11):682-685. 被引量：2
  • 4李星霞,郭澄.木犀草素的药理活性研究[J].中国药房,2007,18(18):1421-1424. 被引量：53
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  • 9Schluns K S, Cook J E, Le P T. TGF-beta differ- entially modulates epidermal growth f actor-mediated increases in leukemia-inhibitory factor, IL-6, IL- 1 alpha, and IL-1 beta in human thymic epithelial cells[J]. J Immunol, 1997, 158(6): 2704-2712.
  • 10Chantry D, Turner M, Feldmann M. et al. Inter- leukin 7 (murine pre-B cell growth factor/lymphopoietinl) stimulates thymocyte growth: regulation by trans- forming growth factor beta[J]. Eur J Immunol, 1989, 19(4): 783-786.

引证文献6

二级引证文献16

国际免疫学杂志
2010年 第6期

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