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椭圆形食管胃吻合术的动物实验及临床研究 被引量:1

Animal experiment and clinic study of elliptical esophagogastroanastomosis
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摘要 目的:为了避免或减少食管癌、贲门癌切除,食管胃吻合术后吻合口狭窄、返流性食管炎及吻合口瘘,设计了食管胃椭圆形吻合术。方法:实验犬40只随机分为A组(椭圆形法)及B组(传统法)进行对照研究。临床上椭圆形吻合法202例,检测60例,传统吻合法106例,检测45例,两组对照分析。结果:A组犬吻合口无狭窄,B组有4只出现狭窄(P<005)。病理学检查:A组愈合过程较B组好;抗返流情况:A组无返流,B组半数以上有返流(P<005)。临床检查吻合口直径:椭圆形法为202±038cm,传统法为135±082cm(P<001);食管粘膜充血、水肿及食管粘液pH值两组对照均有显著意义(P<005)。结论:椭圆形吻合法明显优于传统吻合法,是食管癌、贲门癌切除,食管胃吻合值得应用的手术方法。 Objective: To avoid or reduce anastomotic stenosis leakage and reflux esophagitis of postesophagogastrotomy for patients with carcinoma of esophagus and cardia.We design the elliptical esophagogastromosis. Methods: Forty hybrid dogs were separated into two groups randomly (elliptical anastomosis in 20 and conventional methods in 20).Two hundred and two patients treated with elliptical anastomosis in which 60 cases examined.One hundred and six patients underwent conventional methods and 45 patients tested. Results: There were no anastomotic stenosis in group A dogs and four dogs appear anastomotic stenosis (P<005).The leading capability of anastomosis in group A was better than group B on pathological examination.All dogs were no reflux in group A and over 1/2 dogs were reflux in group B (P<005).The average diameter of anastomosis in elliptical anastomosis was 2. 020.38 cm and conventional methods were 1.350.82 cm (P<001) in all patients.The mucus congestion edema and pH in esophagus were significantly different (P<005) within two groups. Conclusion: Elliptical anastomosis was superior to conventional methods.It was worth poputarizing after esophagogastrostomy for carcinoma of the esophagus and cardia.
出处 《河南医学研究》 CAS 1999年第2期137-139,142,共4页 Henan Medical Research
基金 河南省医学科学院科研基金
关键词 食管癌 贲门癌 食管胃吻合 椭圆形吻合 carcinoma of esophagus carcinoma of cardia esophagogastromosis elliptical anastomosis
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