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乳癌雌激素受体水平与生物学行为的关系

Relationship Between the Level of Estrogen Receptor and Biology Behavior in breast Carcinoma
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摘要 目的探讨病理组织学类型及组织学分级与受体的关系。方法应用乳癌受体酶联雌二醇(ER)与孕酮(PR)亲和组化检测法,检测60例乳癌激素受体分布。结果乳癌激素受体与病理组织学分级及组织学类型相关,组织学分级较低者(分化程度高),ER阳性率高。即受体的阳性率随组织学分级的增高而下降。结论为较准确判断乳癌预后和指导治疗提供参考。 Objective In order to Searoh the relationship between the kind and the grading of pathological histology and receptor in breast carcinoma.Methods The method of enzyme linked estrogen and progesterone receptor immunosorbent histochemistry assay was used to detect the distribution of estrogen receptors and progesterone receptors in tissue of 60 cases of primary breast carcinoma.Results The Results showed that the breast carcinoma receptors were related to the grading and the kind of pathological histology.The positive rate of receptors increases with the descent of the grading of pathological histology.Conclusions It is Suggested that the results can be taken as a reference to accurately judge the prognostication and instruct the treatment of breast carcinoma.
出处 《中国肿瘤临床与康复》 1999年第3期31-32,共2页 Chinese Journal of Clinical Oncology and Rehabilitation
关键词 乳癌 雌激素受 受体 孕酮 生物学行为 breast carcinoma estrogen receptor(ER) progesterone receptor
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参考文献3

  • 1许良中 许世明 等.101例乳腺癌雌激素受体的测定[J].肿瘤,1984,4:18-20.
  • 2陆家齐 陆连荣 等.乳腺癌雌激素受体与病理观察[J].肿瘤防治研究,1984,(11):198-198.
  • 3姚先莹 孟宪钦 等.乳腺癌性类固醇激素受体的检测[J].四川医学院学报,1982,12(2):756-756.

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