摘要
目的探讨肝移植术后缺血性胆道并发症(ischemic-type biliary complications,ITBC)早期肝功能变化特点。方法随访分析肝移植术后BC患者的临床表现,对BC患者早期肝功指标变化进行统计学分析。结果 181例肝移植中发生BC26例(14.36%)。其中缺血性BC11例,9例(81.82%)治疗效果差;BC患者早期ALP、r-GT与TBIL、ALT的增幅出现分离现象;缺血性BC同非缺血性BC早期的TBIL、ALP、r-GT有统计学差异。结论 BC发病早期更高的TBIL、ALP、r-GT血清浓度提示缺血性胆道并发症可能,预后不良。
Objective To explore the characteristic of early changes of liver function in ischemic-type biliary complications（ITBC） after liver transplantation（LT）.Methods Clinical data of 181 patients receiving LT were collected,and results were retrospectively analyzed by follow-up.Early changes of liver function in ITBC were statistically analyzed.Results 26（14.36%,26/181） liver recipients developed BC,including 11 cases of ischemic-type BC,out of which 9（81.82%,9/11）had bad results.Statistical analysis revealed that TBIL,ALT,ALP and r-GT had different increases,and the increases of ALP and r-GT were more obvious.Ischemic-type BC had higher doses of TBIL,ALP and r-GT than other types.Conclusion Higher doses of TBIL,ALP and r-GT at the early phase may be a signal of the occurrence of ITBC,which has a poor prognosis.
出处
《山东大学学报（医学版）》
CAS
北大核心
2010年第10期98-100,共3页
Journal of Shandong University:Health Sciences
关键词
肝移植
胆道并发症
缺血性
肝功能
Liver transplantation
Biliary complication
Ischemic-type
Liver function
