摘要
目的观察高压氧治疗重型颅脑损伤的临床疗效。方法 60例重型颅脑损伤患者随机分为高压氧治疗组(30例)与常规治疗组(30例),两组均予脑损伤常规治疗。高压氧组外加高压氧治疗,每天1次,持续4～70d。比较治疗前和治疗后10d、20d、30d、90d时两组患者脑电图评分和格拉斯哥昏迷评分(GCS),于治疗后90d时进行格拉斯哥结局评分(GOS)。结果与治疗前比较,两组患者治疗后30d起脑电图评分均明显降低;高压氧组治疗后20d起,常规治疗组治疗后30d起,GCS明显增高(均P<0.05)。与常规治疗组比较,高压氧组患者治疗后30d、90d时脑电图评分明显降低;治疗后20d、30d、90d时GCS明显增高(均P<0.05)。高压氧组患者GOS明显高于常规治疗组(P<0.01)。结论重型颅脑损伤患者常规治疗结合高压氧治疗疗效更佳。
Objective To explore the curative effects of hyperbaric oxygen （HBO） for treatment on severe craniocerebral injury. Methods 60 patients with severe craniocerebral injury were randomly divided into HBO group （30 patients） and control group （30 patients） . All of them received basic treatment. The HBO group also treated by HBO once a day with 4 - 70 d. The score of electroencephalography and Glasgow Coma Scale （GCS） were compared pre and 10 d,20 d,30 d,90 d post treatment in the two groups. And Glasgow Outcome Scale （GOS） was tested at 90 d post treatment. Results Compared with pre treatment,the scores of electroencephalography at 30 d,90 d post treatment in the two groups were significantly decreased; while the scores of GCS at 20 d,30 d,90 d post treatment in HBO group,and at 30 d,90 d post treatment in control group were significantly increased （all P 0. 05 ） . Compared with control group,the scores of electroencephalography at 30 d,90 d post treatment in HBO group were significantly decreased; while the scores of GCS at 20 d,30 d,90 d post treatment in HBO group were significantly increased （all P 0. 05） . The score of GOS in HBO group was significantly higher than in control group （P 0. 01） . Conclusion The curative effects on severe craniocerebral injury gets better when basic treatment combined with HBO treatment.
出处
《临床神经病学杂志》
CAS
北大核心
2010年第5期386-388,共3页
Journal of Clinical Neurology
关键词
高压氧
重型颅脑损伤
脑电监测
hyperbaric oxygen
severe craniocerebral injury
electroencephalography monitoring
